For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

Research suggests that consciousness could extend far beyond just humans—every cellular creature in the universe, no matter how big or small, could be conscious, too. Studies show that single-cell ...

Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 ...

Researchers at the Kennedy Institute of Rheumatology have found that physically resisting the formation of an immunological synapse actually promotes a stronger immune response. The findings could ...

We become forgetful as we age. This is often seen as a universal truth, but in fact it is far from universal: some people remain incredibly sharp at ...

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors ...

Scientists at Arc Institute and Stanford University have discovered that age-related memory loss may be driven by changes in the gut rather than the brain itself. In a study published in Nature, ...

A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...

Researchers uncover how SMAD7 directly activates Wnt signaling to promote dental pulp stem cell regeneration CHINA, ...

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...

Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism.

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.