How an RNA-binding protein detects and responds to non-optimal codon usage in human cells

Human genes are written in long strings of three-letter units composed of four different nucleotides. These units—or ...
Infectious Disease Advisor

Little Evidence of Drug-Drug Effects Between DOACs and COVID-19 Antivirals in AF

In patients with AF and COVID-19 who receive DOAC, 30-day mortality risk is similar for nirmatrelvir/ritonavir and RdRp inhibitors.

New international study traces plant viruses back to the last Ice Age

Recent research findings indicate that many of the plant pathogens affecting agriculture today originated during an earlier era than originally believed. Analysis performed by an international team ...
Morning Overview on MSN

Single intramuscular shot shows promise for faster heart attack recovery

A single intramuscular injection of a self-amplifying RNA therapy produced weeks of heart-protective protein in rat models of myocardial infarction, according to a study published in Science on March ...
GitHub

Data Analysis for "A fold switch regulates conformation of an alphavirus RNA-dependent RNA polymerase"

This repository contains the computational data analysis for the study investigating the conformational regulation of alphavirus RNA-dependent RNA polymerase (RdRp) through a fold switch mechanism.
News Medical

Single-cell RNA sequencing reveals accelerated T cell aging in viral infections

A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV." In this study, ...
Phys.org

Could the discovery of a tiny RNA molecule explain the origins of life?

One of the greatest mysteries of our planet is how a soup of lifeless chemicals transformed into the first living cell. There are several competing theories about where this happened, from frozen ...
eLife

Ribosomal RNA synthesis by RNA polymerase I is subject to premature termination of transcription

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...
New Scientist

RNA strand that can almost self-replicate may be key to life's origins

According to the RNA world hypothesis, life began when RNA molecules evolved the ability to make more copies of themselves. Now we have discovered an RNA molecule that is almost capable of this – it ...
The Conversation

RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Marlene Belfort does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...
Frontiers

Editorial: Proceedings of the first RdRp Summit

This Research Topic, “Proceedings of the first RdRp Summit”, was compiled by inviting contributions from participants of the first RdRp Summit related to RNA-dependent RNA polymerase (RdRp) of RNA ...