A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

A metabolic enzyme also binds and unwinds RNA to promote translation of cell cycle genes. This dual role links energy status ...

A simulated cell in the early stages of division. Left half shows membrane (green cubes), and ribosomes (yellow/purple) interwoven through in the cell’s chromosome (red). Right side shows all the ...

Hypertrophic scarring affects a large proportion of patients following burns, trauma, or surgery and arises from prolonged fibroblast hyperactivity and excessive extracellular matrix accumulation.

When a virus infects a bacterial cell, the viral genome is the first component to be fully injected into the cell, making it an ideal immune target. A bacterial enzyme anchored to the membrane ...

An international team led by researchers from the University Medical Center Göttingen (UMG), Germany, has used advanced ...

Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 ...

Ractigen Therapeutics, a pioneering clinical-stage biotechnology company developing innovative small activating RNA (saRNA) therapeutics, today announced that China's National Medical Products ...

Preclinical evidence supports azenosertib ADC combinations as potential promising therapeutic strategies for Triple-Negative Breast Cancer ...

Biotheryx, Inc., a biopharmaceutical company focused on the discovery and development of first-in-class protein degraders for cancer and inflammatory diseases, today announced that the first patient ...

A growing field of research suggests that some medical treatments, such as cancer therapy or vaccines, might be more effective when given at certain times of the day ...