A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

All complex biological systems—like the DNA, RNA and proteins constantly being copied and built within our cells—are prone to errors. That means as life evolved to be more elaborate, it also had to ...

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a ...

After getting engaged, the only words journalist Mrinali Dhembla expected to hear were “I do.” Instead, she was told, “You have cancer.” “When I first heard the words, ‘You have cancer,’ I was ...

Mrinali Dhembla, 27, diagnosed with stage-3 colorectal cancer and Lynch syndrome, recovers rapidly after receiving a dual immunotherapy regimen.

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Mutation rate, as a biological process, denotes the frequency at which heritable changes in nucleotide sequence arise per genome, gene, or nucleotide per cell division or per unit time, driven by ...

A study explains how broken DNA during cell division can trigger chromoanasynthesis when two repair pathways combine, causing ...