Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in ...

Researchers have developed a new strategy that allows engineered T cells to recognize and respond to a single tumour antigen ...

Ryan Notti (left) and Thomas Walz (right) discovered new characteristics of a T cell receptor that are essential to a variety ...

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor ...

In a new study published in GEN’s sister peer-review journal, GEN Biotechnology, titled, “Exploring Structure-Function Relationships in Engineered Receptor Performance Using Computational Structure ...