Avenue Biosciences received $5.7 million in seed extension to scale a high-throughput protein engineering technology designed to accelerate the discovery of protein-based tools and therapies. Balnord ...

Microorganisms, such as baker's yeast, can be used as cell factories to produce different chemicals and proteins, such as commonly used pharmaceuticals as insulin. By modifying the cell factories ...

Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

A novel reporter protein has been developed to enable the investigation of protein biogenesis in the ER and its disruption in disease. A recent research collaboration between multiple Japanese ...

Osaka, Japan – Our cells carry out hundreds of thousands of important functions every day, all of which are carefully orchestrated at a microscopic scale. However, the precise mechanisms that ...

Northwestern investigators have identified a novel approach to control the hierarchical assembly of protein pathways with DNA, according to a study published the Proceedings of the National Academy of ...

RNAs are modified with diverse chemical groups, ranging from simple methyl groups to more complex moieties. These modifications are essential to their diverse roles as catalysts, structural scaffolds, ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.