This article discusses current methods of endotoxin testing, its importance to the industry, sustainability issues relating to the process, and best practices. The potentially devastating effects of ...

SOUTH ORANGE, NJ, Oct. 13, 2020 (GLOBE NEWSWIRE) -- via NewMediaWire-- Nephros, Inc. (Nasdaq: NEPH), a commercial-stage company that develops and sells high performance water purification products and ...

Novel Approach to Achieving Consistent Results with the Limulus Amebocyte Lysate Test The standard tool for screening endotoxins—highly toxic, heat-stable lipopolysaccharides that constitute the outer ...

Quote from Orla Cloak, Director of Testing and Informatics Solutions, Lonza BioScience: “This new addition to our established PyroTec® PRO Solution provides laboratories with greater ability to reduce ...

Understanding the relative strengths and weaknesses of different endotoxin test methods is crucial to maintaining quality and patient safety. Endotoxins are small, hydrophobic molecules that are part ...

As thoroughly covered in your recent article (C&EN, Oct. 28, 2024, page 26), the issue of replacing the traditional natural product test for endotoxin, limulus amoebocyte lysate (LAL), with a ...

The novel Sievers Eclipse BET platform reduces endotoxin assay setup time by as much as 85% and decreases the use of Limulus Amebocyte Lysate (LAL) reagent by up to 90%. At the same time, it fulfills ...

The World Health Organization (WHO) has published its new 2025 Guidelines on the replacement or removal of animal tests for the quality control of biological products.

Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.

The presence of harmful bacteria in parenteral drugs or implantable devices can cause inflammatory responses such as fever and, in some cases, may even be fatal. As a result, robust bacterial ...