Intestinal stem cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for ...

Specifically, the team confirmed that increased expression of cytoskeleton-binding and actin-binding proteins leads to a stable restructuring of the internal cellular architecture. This provides the ...

Human organoids are 3D cell cultures derived from adult stem cells and maintain the variable distribution of epithelial cells seen in primary tissue. They can recapitulate the mechanisms of epithelial ...

Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity ...

Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the ...

On the left: Model organism fruit fly (Drosophila melanogaster), gastrointestinal tract highlighted in green. On the right: Microscope images of the fruit fly intestine where cell nuclei are stained ...

Using human intestinal organoids, scientists uncovered a previously unknown immune function of M cells. By presenting gluten ...

During drug development, researchers need to perform adequate nonclinical testing to ensure a drug’s safety and efficacy before starting clinical trials. An important aspect they must evaluate is a ...

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In ...

Eating is one of life’s few constants: If you’re not eating right now, you’ll certainly be eating something within a few hours. But when and how often we should eat is still not fully understood.