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Novel gene regulation therapy passes key clinical milestone
Groundbreaking Phase 1/2a clinical trials co-led by Linda Laux, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago ...
A Phase I/IIa clinical trials co-led by Linda Laux, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago, show that ...
A new clinical trial led in part by a Lurie Children’s Hospital doctor is showing promise for children with Dravet syndrome, a severe form of epilepsy, and could become the first gene regulation ...
CHARGE syndrome is a complex congenital disorder that presents with a spectrum of multisystem anomalies, including ocular coloboma, choanal atresia, congenital heart defects, and ear malformations, as ...
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in ...
DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...
A massive genomics effort has identified thousands of single nucleotide non-coding variants, which alter gene activity, that link to disease and health.
Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and epigenetic state. By analyzing thousands of sequences, the method showed that ...
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Promoters and enhancers: Tool catches gene-controlling DNA sequences doing each other's jobs
Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...
A team led by UC Davis poultry scientist Huaijun Zhou has created the first comprehensive map of gene regulation in breeds of chickens. The map could be a resource for finding resistance to H5N1 ...
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A Gene Mutation Lets You Function Perfectly on 4 Hours of Sleep. It Might Be in Your DNA.
Without 8 or 9 hours of sleep, most of us end up staggering around like zombies. But according to a new study, some people have a genetic mutation that makes them feel perfectly alive after sleeping ...
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