Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that ...

A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...

Real image of DNA molecules being copied in human cells, visualized by immunofluorescence microscopy. The yellow arrows mark where replication begins, and the white arrows indicate the direction in ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

Cardiff University researchers discovered how a particularly severe type of DNA damage occurs, giving fresh insight into mutation mechanisms that contribute to cancer and inherited genetic diseases.

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

Live imaging of embryos at different stages. Chromosomes are labeled in magenta. 4-cell sister blastomeres are shown, along with 3D-reconstructed images of 2-to-4-cell and 4-to-8-cell divisions.