Nature

How effective are cytogenetic techniques at detecting chromosomal changes?

Several mechanisms by which chromosomal aberrations arise are shown in two normal diploid genomes. Aberrations that lead to alterations in gene number or sequence are illustrated in panel A.
Nature

Risk-based classification of leukemia by cytogenetic and multiplex molecular methods: results from a multicenter validation study

Myeloid neoplasms and acute leukemias encompass many clinically independent entities, some with unique genetic features and optimized treatment approaches. The accurate assignment of patients to ...
GEN

Molecular Cytogenetic Tools

Traditional cytogenetic techniques for the macro-analysis of chromosomal structure often preclude high-resolution visualization of specific genomic regions. Accordingly, researchers are increasingly ...
ascopubs.org

Fluorescence In Situ Hybridization on Peripheral-Blood Specimens Is a Reliable Method to Evaluate Cytogenetic Response in Chronic Myeloid Leukemia

PATIENTS AND METHODS: In a first attempt, we analyzed 62 bone marrow specimens using interphase FISH and compared the results with those of conventional cytogenetics. In a second step, we analyzed 60 ...
Seeking Alpha

Publication Recommends OGM for Analysis of Hematological Neoplasms Due to Streamlined Structural Variant Detection and High Concordance with Traditional Cytogenetic Methods

SAN DIEGO, Nov. 03, 2022 (GLOBE NEWSWIRE) -- Bionano Genomics, Inc. (BNGO) today announced the first published validation study to evaluate the performance of optical genome mapping (OGM) versus ...
Nasdaq

Bionano’s Symposium 2024 Featured Presentations from its Global User Community Highlighting OGM as a Powerful Alternative to Classical Cytogenetics and Strong Complement to NGS

“We were impressed by the engagement at our 2024 Symposium and are excited by the accomplishments of the global researchers who presented their OGM data during sessions and in scientific posters,” ...
manilatimes

Bionano Announces French Publication of an Effective Method for Analysis of Multiple Myeloma by OGM

SAN DIEGO, April 08, 2025 (GLOBE NEWSWIRE) -- Bionano Genomics, Inc. (Nasdaq: BNGO) today announced a study published in The Journal of Molecular Diagnostics that describes a method for analysis of ...
Business Insider

Bionano Genomics Releases Users’ Video Presentations of Preliminary Data Affirming Saphyr's Potential to Replace Traditional Cytogenetics Methods in Certain Blood Cancers

SAN DIEGO, Aug. 30, 2019 (GLOBE NEWSWIRE) -- Bionano Genomics, Inc. (NASDAQ: BNGO), a life sciences instrumentation company that develops and markets Saphyr ®, a platform for ultra-sensitive and ultra ...