Two decades after the human genome sequence was completed, researchers have finally finished a map of the piece that makes males distinct. The Y chromosome is what distinguishes biological males from ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

In what might be a surprise for some, the male sex chromosome is far more complex than its female counterpart. This is why it’s taken scientists so long to work out exactly what makes a male a male.

The work of Thomas Hunt Morgan defined the earliest steps in mapping genes to chromosomes. Work from his lab defined the first sex-linked traits, crossing over, linkage, recombination rates and ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Virginia Tech entomologists have developed a chromosome map for about half of the genome of the mosquito Aedes agypti, the major carrier of dengue fever and yellow fever. With the map, researchers can ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...