Two decades after the human genome sequence was completed, researchers have finally finished a map of the piece that makes males distinct. The Y chromosome is what distinguishes biological males from ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Researchers identified three chromosome 21 genes that are overactive in brain cells of individuals with Down syndrome, and demonstrated partial molecular correction using antisense oligonucleotides.

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

In what might be a surprise for some, the male sex chromosome is far more complex than its female counterpart. This is why it’s taken scientists so long to work out exactly what makes a male a male.

Virginia Tech entomologists have developed a chromosome map for about half of the genome of the mosquito Aedes agypti, the major carrier of dengue fever and yellow fever. With the map, researchers can ...

The work of Thomas Hunt Morgan defined the earliest steps in mapping genes to chromosomes. Work from his lab defined the first sex-linked traits, crossing over, linkage, recombination rates and ...

Studies show aging men often lose the Y chromosome in some cells, a change now linked to heart disease, cancer, and shorter ...

This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...