The study shows that fat tissue, when processed and cultured in a specific way, can self-organize into structures resembling ...

Researchers have grown tumor organoids -- three-dimensional miniature tumors in the laboratory -- that mimic the different structures and characteristics of pancreatic cancer. The scientists ...

A study using organoids derived from patients' pancreatic cancer tissues revealed that a subset of highly aggressive form of pancreatic cancer, called adenosquamous carcinoma, develop from a less ...

A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue.

Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

Organoids are 3D cell culture models that more accurately reflect the structural and functional complexities of organs in vitro than traditional 2D cell culture methods. Generally derived from stem ...

Cryptic peptides, which are expressed in pancreatic cancer cells, could be promising targets for T-cell therapies that attack pancreatic tumors, according to a new study. Researchers from MIT and Dana ...

Bioengineered organs are no longer just structural substitutes. A new review published in Trends in Biotechnology introduces a groundbreaking concept: biohybrid-engineered tissue (BHET) ...

A new study describes a unique bioengineered tissue construct, or organoid, into which colorectal cancer cells are embedded, creating a model of the tumor and surrounding extracellular matrix (ECM).